Link to my Bibliography

PUBLICATIONS

•  [8] Digvijay Singh, Yanbo Wang, John Mallon, Olivia Yang, Jingyi Fei, Anustup Poddar, Damon Ceylan, Scott Bailey, Taekjip Ha.
"Mechanism of improved specificity of engineered Cas9s revealed by single molecule analysis". 
Nature Structural and Molecular Biology (2018)
Pre-print

•  [7] Digvijay Singh, John Mallon, Anustup Poddar, Yanbo Wang, Ramreddy Tipanna, Olivia Yang, Scott Bailey, Taekjip Ha.
"Real-time observation of DNA target interrogation and product release by RNA-guided endonuclease CRISPR-Cpf1".
PNAS (2018). 
Pre-print

•  [6] Digvijay Singh, Taekjip Ha.
"Understanding the molecular mechanism of CRISPR toolbox using single-molecule approaches".
ACS Chemical Biology (2018). 

•  [5] Boyang Hua, Yanbo Wang, Kyu Young Han, Seongjin Park, Digvijay Singh, Jin H. Kim, Wei Cheng, Taekjip Ha.
"Single-molecule centroid localization algorithm improves the accuracy of fluorescence binding assays".
Biochemistry (2018)

•  [4] Digvijay Singh, Samuel H. Sternberg, Jingyi Fei, Jennifer A. Doudna, Taekjip Ha.
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9”. 
Nature Communications. (2016). 
Pre-print

•  [3] Jingyi Fei, Digvijay Singh, Qiucen Zhang, Seongjin Park, Divya Balasubramanian, Ido Golding, Carin K. Vanderpool, Taekjip Ha. “Determination of in vivo target search kinetics of regulatory non-coding RNA”. 
Science. (2015).

•  [2] Boyang Hua, Kyu Young Han, Ruobo Zhou, Hajin Kim, Xinghua Shi, Sanjaya C. Abeysirigunawarden, Ankur Jain, Digvijay Singh, Vasudha Aggarwal, Sarah A. Woodson, Taekjip Ha.
An improved surface passivation method for single-molecule Studies”. 
Nature Methods. (2014).

•  [1] A. Dhar, K. Girdhar, D. Singh, S. Ebbinghaus and M. Gruebele. “Different protein stability and folding kinetics in the nucleus, endoplasmic reticulum, and cytoplasm of living cells”. 
Biophys. J. 101, 421-430 (2011).

CONFERENCE PROCEEDINGS

•  Yanbo Wang, Digvijay Singh, John Mallon, Boyang Hua, Scott Bailey, Taekjip Ha. “Simultaneous Real-Time Observation of DNA Unwinding and Nuclease Domain Activation in Cas9-RNA-DNA Complex via Three-Color Single Molecule FRET”. Biophysical Society Meeting (2018).

• Digvijay Singh, Yanbo Wang, John Mallon, Samuel H. Sternberg, Olivia Yang, Jingyi Fei, Anustup Poddar, Damon Ceylan, Jennifer A. Doudna, Scott Bailey, Taekjip Ha. "Mechanistic basis of the specificity improving mutations of Engineered Cas9s". NCI RNA Biology (2017).

Digvijay Singh, Yanbo Wang, John Mallon, Samuel H. Sternberg, Olivia Yang, Jingyi Fei, Anustup Poddar, Damon Ceylan, Jennifer A. Doudna, Scott Bailey, Taekjip Ha. "Mechanistic basis of the specificity improving mutations of Engineered Cas9s". Chesapeake Bay Area Single Molecule Meeting (2017).

• Li Dai, Digvijay Singh, Reza Vafabakhsh, Marthandan Mahalingam, Vishal Kottadiel, Yann Chemla, Taekjip Ha, Venigalla B Rao. "Mechanism of coordination of the bacteriophage T4 DNA packaging motor analyzed by real-time single molecule fluorescence assay". Biophysical Society Meeting (2016)

• Digvijay Singh, Samuel H. Sternberg, Jingyi Fei, Jennifer A. Doudna, Taekjip Ha. "Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9". Biophysical Society Meeting (2016)

• Boyang Hua, Ruobo Zhou, Hajin Kim, Xinghua Shi, Ankur Jain, Digvijay Singh, Vasudha Aggarwal, Taekjip Ha. "An improved surface passivation method for single-molecule studies". Biophysical Society Meeting (2014)

• Seongjin Park, Sultan Doǧanay, Jingyi Fei, Digvijay Singh, Taekjip Ha. "Super-resolution imaging of immune response proteins against viral infection". Biophysical Society Meeting (2014)

• Jingyi Fei, Digvijay Singh, Qiucen Zhang, Seongjin Park, Ido Golding, Carin K Vanderpool, Taekjip Ha. "Watching gene regulation by small RNA in bacteria with super-resolution imaging". Biophysical Society Meeting (2013)

• Jingyi Fei, Seongjin Park, Digvijay Singh, Yanxin Liu, John E. Stone, Klaus Schulten, Kannanganattu V.Prasanth and Taekjip Ha. "Organization of long non-coding RNAs in nuclear bodies revealed by super-resolution imaging". EMBO | EMBL Symposia: The Complex Life of mRNA (2012)