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Digvijay Singh
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Cryo-Focused Ion Beam Milling of Cells
The Molecular Architecture of the Nuclear Basket
Integrative spatiotemporal map of nucleocytoplasmic transport
Comprehensive structure and functional adaptations of the yeast nuclear pore complex
A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein
Real-time observation of Cas9 postcatalytic domain motions
Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography
Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding
Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a)
Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis
Understanding the Molecular Mechanisms of the CRISPR Toolbox Using Single Molecule Approaches
The Single-Molecule Centroid Localization Algorithm Improves the Accuracy of Fluorescence Binding Assays
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
Determination of in vivo target search kinetics of regulatory noncoding RNA
An Improved Surface Passivation Method for Single-Molecule Studies
Protein stability and folding kinetics in the nucleus and endoplasmic reticulum of eucaryotic cells
paper
Cryo-Focused Ion Beam Milling of Cells
The Molecular Architecture of the Nuclear Basket
Integrative spatiotemporal map of nucleocytoplasmic transport
Comprehensive structure and functional adaptations of the yeast nuclear pore complex
A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein
Real-time observation of Cas9 postcatalytic domain motions
Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography
Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding
Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a)
Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis
Understanding the Molecular Mechanisms of the CRISPR Toolbox Using Single Molecule Approaches
The Single-Molecule Centroid Localization Algorithm Improves the Accuracy of Fluorescence Binding Assays
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
Determination of in vivo target search kinetics of regulatory noncoding RNA
An Improved Surface Passivation Method for Single-Molecule Studies
Protein stability and folding kinetics in the nucleus and endoplasmic reticulum of eucaryotic cells
blog
Good vs. bad or right vs. wrong
The worst "favorable" peer-review of all time ?
news
Proposal for Parenthood accepted
misc
Talks
Molecular Sociology
through
in situ
structure, assembly and function
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Molecular Sociology
through
in situ
structure, assembly and function
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Digvijay Singh
Section of Molecular Biology
University of California, San Diego
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